Publications
Luke S, Tewari R, Silberklang M (2008): Development and validation of a histological assay for tissue-engineered OrCel Bilayered Cellular Matrix (Manuscript in preparation)
Chimanji N, Tewari R, Luke S, Silberklang M (2008): In vitro evidence for the histocompatibility of the allogenic cells in cultured skin substitutes, OrCel Bilayered Cellular Matrix (Manuscript in preparation)
Windsor M, Wilson C, Tewari R, Chimanji N, Luke S, Eisenberg M, Moore G, Philip M, Silberklang M (2008): A novel healing model in the SCID mouse applied to the therapeutic cultured device, OrCel-Bilayered Cellular Matrix (Manuscript in preparation)
Marx G, Levdansky L, Silberklang M, Thomas D, Hoffman N, Luke S, Lesnoy D, Gorodetsky R (2008): Haptide-coated collagen sponge as a bioactive matrix for tissue regeneration: J Biomed Mater Res 84(2):571-583
Huang NF, Gupta M, Luke S (2006): Detection of genetic abnormalities in ovarian carcinomas (textbook chapter). In Handbook of Immunohistochemistry and in situ hybridization of human carcinomas: Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma, Volume 4 Elsevier Sciences Press NY)
Thomas D, Huang NF, Luke S (2005): Stem cell therapeutics for cardiac repair. Ind. J Multi. Res 1 (1): 1-12
Eisenbud D, Huang NF, Luke S, Silberklang M (2004): Skin substitutes and wound healing: Current status and challenges. Wounds 16(1): 2-17
Huang NF, Varghese SZ, Luke S (2003): Apoptosis in skin wound healing. Wounds 15 (6): 182-194
Huang NF, Gupta M, Varghese S, Rao S, Luke S (2002): Detection of numerical chromosomal abnormalities in epithelial ovarian neoplasms by fluorescence in situ hybridization and a review of the literature. Appl. Immunohistochem & Mol Morph 10(2): 187-193
Xia J, Gupta M, Preminger B, Varkey JA, Luke S (1999): Small cell carcinoma of the ureter arising in an adult polycystic kidney. A case report with interphase cytogenetics study. Appl. Immunohistochem & Mol Morph 7: 164-168
Luke S, Varkey JA, Belogolovkin V, Ladoulis CT (1997): The current state of the fluorescence in situ hybridization (FISH) in diagnostic pathology. Cell Vision 4: 2-17
Luke S, Belogolovkin V, Varkey JA, Ladoulis CT (1997): Fluorescence in situ hybridization (textbook chapter) p139-173. In Analytical Morphology, Eaton Publications, ΜΑ.
Luke S, Gandhi S, Verma RS (1995): Conservation of DNA synteny of Down syndrome critical region in human and great apes. Gene 161(2): 283-285
Luke S, Verma RS (1995): The genomic sequence for Prader-Willi/Angelman syndromes loci of humans are apparently conserved in the great apes. J Mol. Evol. 41: 250-252
Luke S, Verma RS (1995): Human and Chimpanzee share ancestral centromeric alpha satellite DNA sequences but other fractions of heterochromatin differ considerably. Am J Phy. Antro. 96: 63-71
Conte RA, Luke S, Verma RS (1995): Enumeration of seminal leukocytes by fluorescence in situ hybridization.
Conte RA, Luke S, Verma RS (1995): Characterization of ring chromosome 21 by FISH technique. Clin Genet 48 (4): 188-191
Verma RS, Luke S, Conte RA (1994): FISH technique: what's all the fuss about. Genet. Anal. Tech. Appl 11 (4): 106-109.
Verma RS, Luke S (1994): Evolutionary divergence of human chromosome 9 as revealed by the position of ABL protooncogene in higher primates. Mol. General Genet 243 (4): 369-373.
Luke S, Birnbaum R, Verma RS (1994): A double hybridization for localization of centromeric and telomeric repeat sequences in nonagenarians. Genet. Anal. Tech. Appl 11(3): 77-80
Luke S, Verma RS, Conte RA, Luke S (1994): Identification of Prader-Willi Locus in an isodicentric marker chromosome. Am. J. Med. Genet 51: 232-233
Verma RS, Giridharin R, Conte RA, Luke S (1994): An apparent balanced translocation between chromosomes 7 and 13 in a 47, XYY individual. Jpn J Hum Genet 39 (4): 451-452
Verma RS, Conte RA, Mathews T, Luke S (1994): Monozygotic twinning in a female with triple X (47, XXX). Gynecol Invest 37: 279-280.
Luke S, Aggarwal G, Stetka DG, Verma RS (1994): Alphoid diversity of a so-called monocentric Robertsonian fusion. Chromo Res 2: 73-75
Luke S, Verma RS (1993): The genomic synteny at the DNA level between human and chimpanzee chromosomes. Chromo. Res 1: 215-219.
Verma RS, Luke S, Brennan JP, Matthews T, Conte RA, Macera MJ (1993): Molecular topography of the secondary constriction region (qh) of human chromosome 9 with unusual euchromatic band. Am. J. Hum. Genet 52: 981-986
Luke S, Verma RS (1993): Telomeric repeat (TTAGGG) sequences of human chromosomes are conserved in chimpanzee. Mol. Gen 237: 460-462.
Luke S, Verma RS (1993): Telomeric repeat (TTAGGG)n sequences of human chromosomes are conserved in chimpanzee. Mol. Gen. Genet 237: 460-462.
Luke S, Verma RS (1993): Genetic consequences of euchromatic band within 9qh region. Am J. Med. Genet 45: 107.
Luke S, Verma RS (1992): Chromosomal domains of chimpanzee are diverged from human as revealed by in situ hybridization using human genomic probe. Hum. Evol. 7: 71-74.
Verma RS, Luke S, Conte RA (1992): Molecular characterization of the smallest secondary constriction region (qh) of the human chromosome 16. GATA 9: 140-142.
Luke S, Verma RS, Conte RA, Mathews T (1992): Molecular characterization of the secondary constriction region of the human inverted chromosome 9 by fluorescence in situ hybridization. J. Cell Sci 103 (4): 919-923.
Verma RS, Conte RA, Luke S, Sindwani V, Macera MJ (1992): Deciphering the fluorescence variability of human genomic heterochromatin by DA/DAPI technique. Clin Genet 42: 267-270.
Luke S, Mathews T, Verma RS (1992): Evolution of pericentromeric heterochromatin of the human X-chromosome. Genetica 87: 63-64.
Luke S, Verma RS (1992): Origin of human chromosome 2. Nature Genet 2: 11-12.
Verma RS, Luke S (1992): Variations in alphoid DNA sequences escape detection of aneuploidy at interphase by FISH technique. Genomics 14: 113-116.
Conte RA, Luke S, Verma RS (1992): Molecular characterization of inverted pericentromeric heterochromatin of chromosome 3. Histochemistry 97: 509-510.
Luke S, Verma RS (1992): Detection of the heteromorphic spectrum of heterochromatin in the human genome by in situ digestion using restriction endonuclease AluI. Am. J. Med. Genet 43: 1026-1029.
Verma RS, Conte RA, Pitter JH, Luke S (1992): A rare chromosomal abnormality involving pericentric inversion of chromosome 7 and ring chromosome 8 in a girl with minor anomalies. J. Med. Genet 29: 66-67.
Luke S, Bennett HS, Pitter JH, Verma RS (1992): A new case of monosomy for 17q25 qter due to a maternal translocation [t(3;17) p12;q24]. Ann. Genet 35: 48-50.
Verma RS, Luke S, Dhawan P (1992): Twins with two different fathers. Lancet 339: 63-64.
Verma RS, Luke S (1991): Heteromorphisms of pericentromeric heterochromatin of chromosome 19. GATA 8 (6): 179-180.
Luke S, Verma RS (1991): Pericentromeric heterochromatin of chromosome 3. J. Med. Genet 28:805-808.
Verma RS, Luke S, Conte RA, Macera MJ (1991): A so-called rare heteromorphism of the human genome. Cytogenet Cell Genet 56: 63.
Luke S, Verma RS (1991): Detection of heteromorphic markers by AluI digestion of human metaphase chromosomes and its resistance to CBG and DA/DAPI variants of chromosome 9. Appl. Cytogenet 17(2): 28-32.
Luke S, Verma RS, PeBenito R, Macera MJ (1991): Inversion-duplication of bands q13-q21 of human chromosome 9. Am J Med Genet 40: 57-60.
ABSTRACTS & INTERNATIONAL PRESENTATIONS:
Tewari R, Luke S, Lesnoy D, Burke T, Silberklang M (2004): Histological Analysis of the Collagen sponge component of a tissue-engineered skin substitute (Presentation @ Biomedical Engineering Society Annual Meeting in Philadelphia).
Chimanji N, Tewari R, Luke S, Silberklang M (2004): In vitro evidence for the histocompatibility of the allogenic cells in a cultured skin substitute, OrCel Bilayered Cellular Matrix (Presentation @ 19th Symposium for Advanced Wound Care in Orlando, FL).
Windsor M, Wilson C, Tewari R, Chimanji N, Luke S, Eisenberg M, Moore G, Philip M, Silberklang M (2003): A novel healing model in the SCID mouse applied to the therapeutic cultured cell device, OrCel-Bilayered Cellular Matrix (Presentation @ 5th International Tissue Engineering Society Meeting in Orlando, Florida).
Luke S, Xia J, Thomas R, Chaudhri P, Gupta M, Ladoulis CT (1998): Comparison of flow cytometry vs AgNOR for estimating DNA aneuploidy and cell proliferation in breast carcinoma (Presentation @ 3rd Annual Multidisciplinary Symposium on Breast Disease, Amelia Island, Florida).
Varkey JA, Luke S, Xia J, Gupta M, Ladoulis CT (1998): Analysis of the rate of proliferation and apoptotic index in human lobular breast carcinomas (Presentation @ 3rd Annual Multidisciplinary Symposium on Breast Diseases, Amelia Island, Florida).
Luke S, Thomas R, Chaudhari P, Xia J, Gupta M, Ladoulis C (1997): Correlation of c-erb B2 gene amplification and chromosomal aneuploidy in ductal carcinoma of the breast. Am. J. Clin. Path 107: 479 (Presentation @ American Society of Clinical Pathologists, Chicago).
Luke S, Thomas R, Chaudhari P, Xia J, Gupta M, Ladoulis C (1997): Chromosomal Aneuploidy detected by fluorescence in situ hybridization (FISH) in in situ ductal carcinoma of the breast. Am. J. Clin. Path 107: 479 (Presentation @ American Society of Clinical Pathologists).
Varkey JA, Chaudhari P, Gupta M, Luke S, Ladoulis CT (1997): Molecular histopathological analysis of signet cell carcinoma of the sigmoid colon. Am J. Hum. Genet 47: 2113.
Luke S, Shepelsky M (1997): FISH: recent advances and diagnostic aspects (Presentation @ International Conference on Molecular Morphology at University of Florida, Proc 36-40).
Luke S, Huang NF, Goyal N, Varkey JA, Oculam AA, Gupta M, Ladoulis CT (1997): Optimization of fluorescence in situ hybridization in cytological specimens (Presentation @ International Conference on Molecular Morphology, University of Florida, Proc 84-85).
Menon S, Luke S, Solish G (1995): Polymorphism and cross-hybridization – pitfalls in aneuploidy enumeration by fluorescence in situ hybridization. Am J. Clin. Path 104(3): 328 (Presentation @ American Society of Clinical Pathologists).
Lester P, Luke S, Verma RS (1993): A novel method for estimating interphase stages using human genomic painting. Am. J. Hum. Genet 53(3): A576.
Agarwal G, Luke S, Verma RS (1993): Hybridization spectrum of the human genome using chromosomes 13/21 alphoid probe. Am. J. Hum. Genet 53(3): A521.
Conte RA, Luke S, Verma RS (1993): Molecular characterization of a ring chromosome 21 in Down syndrome. Am. J. Hum. Genet 53(3): A536.
Girisdharan R, Conte RA, Luke S, Macera MJ, Verma RS (1993): Molecular characterization of a marker chromosome in an individual with hypotonia and global developmental delay. Am. J. Hum. Genet 53(3): A551.
Luke S, Verma RS (1993): Evolutionary mechanism of Prader-Willi locus through inversion in chimpanzee. Am. J. Hum. Genet 53(3): A874.
Brennan JP, Verma RS, Luke S, Conte RA, Macera MJ (1992): Origin of extra G-positive band within the 9qh region. Am. J. Hum. Genet 51(4): A1232.
Mathew T, Luke S, Verma RS (1992): Rapid diagnosis of chromosomal abnormalities in fetal loss. Am. J. Hum. Genet 51(4): A1622.
Verma RS, Luke S (1992): Pitfalls of fluorescence in situ hybridization. Am. J. Hum. Genet 51(4): A1541.
RESEARCH GRANTS
Co-investigator, "Transplacental tumorigenesis by AZT in mice," PIs: Jiang Gu, M.D., Ph.D., and L.M. Andreson, Ph.D., Maimonides and Downstate Medical Center, Brooklyn. Amount: $700,000, NIH. 1997
Principal Investigator, "The relationship of oncogene mutations and overexpression in breast cancer staging." Amount: $45,000, Maimonides Research & Development Foundation, NY. 1996
Co-investigator, "Evaluation of prognostic markers and tumor progression in epithelial ovarian carcinomas," PI: Mala Gupta, M.D. Amount: $30,000, Maimonides Research & Development Foundation. 1996
Co-investigator, "The Prostate, Lung, Colon, and Ovarian Cancer Screening Trial" (PLCO) for Brooklyn, National Cancer Institute. Amount: $70,000, PI: Sameer Rafla, M.D., Ph.D., Cancer Institute of Brooklyn at Maimonides Medical Center, Brooklyn. 1995
Principal Investigator, "Evolution of loss of heterozygosity among breast and ovarian tumors." Amount: $62,500, Maimonides Research Foundation, Brooklyn. 1995
Co-investigator, "Fibronectin in Amniotic Fluid." Amount: $30,284, PI: George Solish, M.D., Ph.D., Maimonides Research Foundation. 1995
WORKSHOPS AND COLLOQUIUMS
(Several international seminars and workshops)
Interphase cytogenetics in diagnostic genetics
Fluorescence in situ hybridization (FISH) in surgical pathology
Evaluation of HER2/neu gene amplification in breast cancer as a prognostic marker
Techniques in genetic toxicology
Cell culture for beginners
Basics in stem cell biology and tissue engineering
